User profiles for "author:Samuel Ridout"

Samuel Ridout

Brown University
Verified email at brown.edu
Cited by 1618

Adverse childhood experiences run deep: toxic early life stress, telomeres, and mitochondrial DNA copy number, the biological markers of cumulative stress

KK Ridout, M Khan, SJ Ridout - Bioessays, 2018 - Wiley Online Library
This manuscript reviews recent evidence supporting the utility of telomeres and
mitochondrial DNA copy number (mtDNAcn) in detecting the biological impacts of adverse …

Telomeres, early-life stress and mental illness

SJ Ridout, KK Ridout, HT Kao, LL Carpenter… - Clinical Challenges in …, 2015 - karger.com
Telomeres are structures of tandem TTAGGG repeats that are found at the ends of
chromosomes and preserve genomic DNA by serving as a disposable buffer to protect DNA …

Depression and telomere length: A meta-analysis

KK Ridout, SJ Ridout, LH Price, S Sen… - Journal of affective …, 2016 - Elsevier
Background Several recent studies have investigated the relationship between telomere
length and depression with inconsistent results. This meta-analysis examined whether …

Early life adversity and telomere length: a meta-analysis

KK Ridout, M Levandowski, SJ Ridout, L Gantz… - Molecular …, 2018 - nature.com
Early adversity, in the form of abuse, neglect, socioeconomic status and other adverse
experiences, is associated with poor physical and mental health outcomes. To understand …

Emergency department encounters among youth with suicidal thoughts or behaviors during the COVID-19 pandemic

KK Ridout, M Alavi, SJ Ridout, MT Koshy… - JAMA …, 2021 - jamanetwork.com
Importance Population-level reports of suicide-related emergency department (ED)
encounters among youth during the COVID-19 pandemic are lacking, along with youth …

Age and flow-mediated dilation: a comparison of dilatory responsiveness in the brachial and popliteal arteries

BA Parker, SJ Ridout… - American Journal of …, 2006 - journals.physiology.org
Previous investigations of age-associated changes in flow-mediated vasodilation (FMD) in
women have been limited to the upper extremity and have not accounted for possible age …

Association of telomere length and mitochondrial DNA copy number in a community sample of healthy adults

AR Tyrka, LL Carpenter, HT Kao, B Porton… - Experimental …, 2015 - Elsevier
Cellular aging plays a role in longevity and senescence, and has been implicated in medical
and psychiatric conditions, including heart disease, cancer, major depression and …

5‐Hz transcranial magnetic stimulation for comorbid posttraumatic stress disorder and major depression

NS Philip, SJ Ridout, SE Albright… - Journal of traumatic …, 2016 - Wiley Online Library
Current treatment options for posttraumatic stress disorder (PTSD) offer modest benefits,
underscoring the need for new treatments. Repetitive transcranial magnetic stimulation …

Physician-training stress and accelerated cellular aging

KK Ridout, SJ Ridout, C Guille, DA Mata, H Akil… - Biological …, 2019 - Elsevier
Background Stress is a key precipitant for many common diseases, but established
biological markers to track stress and guide investigations into mechanisms linking stress …

Changes in diagnostic and demographic characteristics of patients seeking mental health care during the early COVID-19 pandemic in a large, community-based …

KK Ridout, M Alavi, SJ Ridout, MT Koshy… - The Journal of …, 2021 - psychiatrist.com
Objective: The early COVID-19 pandemic resulted in great psychosocial disruption and
stress, raising speculation that psychiatric disorders may worsen. This study aimed to …