[HTML][HTML] A long-term mechanistic computational model of physiological factors driving the onset of type 2 diabetes in an individual

…, IE Sheu, M Paich, CM Chelini, PM D'Alessandro… - PLoS …, 2018 - journals.plos.org
A computational model of the physiological mechanisms driving an individual's health towards
onset of type 2 diabetes (T2D) is described, calibrated and validated using data from the …

Interactive multi-user 3d visual analytics in augmented reality

…, A Mower, S Burns, C Chelini, PD Alessandro… - arXiv preprint arXiv …, 2020 - arxiv.org
This publication reports on a research project in which we set out to explore the advantages
and disadvantages augmented reality (AR) technology has for visual data analytics. We …

[HTML][HTML] Optimization of nutritional strategies using a mechanistic computational model in prediabetes: Application to the J-DOIT1 study data

…, A Suganuma, H Kuzuya, S Pandey, P D'Alessandro… - Plos one, 2023 - journals.plos.org
Lifestyle interventions have been shown to prevent or delay the onset of diabetes; however,
inter-individual variability in responses to such interventions makes lifestyle …

[HTML][HTML] A computational platform integrating a mechanistic model of Crohn's disease for predicting temporal progression of mucosal damage and healing

…, RK Suzuki, AL Hamada, PM D'Alessandro… - Advances in …, 2022 - Springer
Introduction Physicians are often required to make treatment decisions for patients with
Crohn’s disease on the basis of limited objective information about the state of the patient’s …

[HTML][HTML] Computational Simulation Model to Predict Behavior Changes in Inflammatory Bowel Disease Patients during the COVID-19 Pandemic: Analysis of Two …

…, K Nakamura, SP Burns, PM D'Alessandro… - Journal of Clinical …, 2023 - mdpi.com
Managing inflammatory bowel disease (IBD) is a major challenge for physicians and patients
during the COVID-19 pandemic. To understand the impact of the pandemic on patient …

Theatre: An innovative teaching tool integrated into core undergraduate medical curriculum

PR D'Alessandro, G Frager - Arts & Health, 2014 - Taylor & Francis
Background: Ed's Story: The Dragon Chronicles is a verbatim play based on the journal of a
16-year-old with advanced cancer and transcripts from 25 interviews conducted after his …

Effect of distance to tertiary centre on enrolment of paediatric patients with relapsed or refractory cancer on early phase clinical trials in British Columbia

PR D'Alessandro, JN Bone, JF Davis… - Paediatrics & Child …, 2023 - academic.oup.com
Objectives Access to early phase trials for children with relapsed, refractory or progressive (RRPD)
cancer is limited in Canada. Patients and families face barriers to access trials, which …

New York City fourth graders who receive a climate change curriculum with hydroponic gardening have higher science achievement scores

…, M Burgermaster, D D'Alessandro, R Paul… - Applied …, 2020 - Taylor & Francis
We compared 2014–15 New York State Science Assessment scores of fourth grade students
who received the New York Sun Works (NYSW) Program (n = 638) with two comparison …

Identification of microRNA-124 as a major regulator of enhanced endothelial cell glycolysis in pulmonary arterial hypertension via PTBP1 (polypyrimidine tract binding …

…, AR Flockton, MG Frid, PD Upton, A D'Alessandro… - Circulation, 2017 - Am Heart Assoc
Background: Pulmonary arterial hypertension (PAH) is characterized by abnormal growth
and enhanced glycolysis of pulmonary artery endothelial cells. However, the mechanisms …

Based Theater in the Pediatric Oncology Setting: Balancing Ethical Tensions

PR D'Alessandro - Qualitative Inquiry, 2023 - journals.sagepub.com
Research-based theater (RbT) in health care and medical education settings generates unique
ethical discourses, particularly when involving pediatric patients. Ed’s Story: The Dragon …