User profiles for "author:M Parker"

Matthew Parker

Oxford Nanopore Technologies, The University of Sheffield
Verified email at sheffield.ac.uk
Cited by 21386

Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock

RP Dellinger, JM Carlet, H Masur, H Gerlach… - Critical care …, 2004 - journals.lww.com
Objective In 2003, critical care and infectious disease experts representing 11 international
organizations developed management guidelines for severe sepsis and septic shock that …

[HTML][HTML] The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis

MM Levy, RP Dellinger, SR Townsend… - Intensive care …, 2010 - Springer
Abstract Objective The Surviving Sepsis Campaign (SSC or “the Campaign”) developed
guidelines for management of severe sepsis and septic shock. A performance improvement …

Septic shock in humans: advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy

JE Parrillo, MM Parker, C Natanson… - Annals of internal …, 1990 - acpjournals.org
Septic shock is the commonest cause of death in intensive care units. Although sepsis
usually produces a low systemic vascular resistance and elevated cardiac output, strong …

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008

RP Dellinger, MM Levy, JM Carlet, J Bion… - Critical care …, 2008 - journals.lww.com
Objective: To provide an update to the original Surviving Sepsis Campaign clinical
management guidelines,“Surviving Sepsis Campaign Guidelines for Management of Severe …

[PDF][PDF] Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus

B Korber, WM Fischer, S Gnanakaran, H Yoon… - Cell, 2020 - cell.com
A SARS-CoV-2 variant carrying the Spike protein amino acid change D614G has become
the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies …

Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States

RS Lanciotti, JT Roehrig, V Deubel, J Smith, M Parker… - Science, 1999 - science.org
In late summer 1999, an outbreak of human encephalitis occurred in the northeastern United
States that was concurrent with extensive mortality in crows (Corvus species) as well as the …

The Genome of the Diatom Thalassiosira Pseudonana: Ecology, Evolution, and Metabolism

EV Armbrust, JA Berges, C Bowler, BR Green… - Science, 2004 - science.org
Diatoms are unicellular algae with plastids acquired by secondary endosymbiosis. They are
responsible for∼ 20% of global carbon fixation. We report the 34 million–base pair draft …

[HTML][HTML] The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction

RJ Kim, E Wu, A Rafael, EL Chen… - … England Journal of …, 2000 - Mass Medical Soc
Background Recent studies indicate that magnetic resonance imaging (MRI) after the
administration of contrast material can be used to distinguish between reversible and …

Profound but reversible myocardial depression in patients with septic shock

MM Parker, JH SHELHAMER… - Annals of internal …, 1984 - acpjournals.org
To characterize the role of cardiac function in septic shock, serial radionuclide
cineangiographic and hemodynamic evaluations were done on 20 patients with …

[HTML][HTML] The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

…, P Gupta, R Huether, RW Kriwacki, M Parker… - Nature, 2012 - nature.com
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive
malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP …