Evolution of a manufacturing route to omarigliptin, a long-acting DPP-4 inhibitor for the treatment of type 2 diabetes
JYL Chung, JP Scott, C Anderson… - … Process Research & …, 2015 - ACS Publications
Development of a convergent synthesis of omarigliptin (MK-3102) suitable for commercial
manufacture is described. The target molecule is assembled through a diastereoselective …
manufacture is described. The target molecule is assembled through a diastereoselective …
Visionary medicine: speculative fiction, racial justice and Octavia Butler's 'Bloodchild'
JC Pasco, C Anderson, S DasGupta - Medical humanities, 2016 - mh.bmj.com
Medical students across the USA have increasingly made the medical institution a place for
speculating racially just futures. From die-ins in Fall 2014 to silent protests in response to …
speculating racially just futures. From die-ins in Fall 2014 to silent protests in response to …
Unmasking of anti-ribosomal P autoantibodies in healthy individuals.
HA Stafford, CJ Anderson, M Reichlin - Journal of immunology …, 1995 - journals.aai.org
Autoantibodies to the ribosomal P proteins (anti-P) are found almost exclusively in a subset
of patients with systemic lupus erythematosus. To determine if anti-P autoantibodies are …
of patients with systemic lupus erythematosus. To determine if anti-P autoantibodies are …
Anti-idiotypic antibodies prevent the serologic detection of antiribosomal P autoantibodies in healthy adults.
ZJ Pan, CJ Anderson, HA Stafford - The Journal of clinical …, 1998 - Am Soc Clin Investig
A subset of SLE patients has serologically detectable autoantibodies to the ribosomal P
proteins (anti-P). We reported the discovery of covert anti-P antibodies and their masking …
proteins (anti-P). We reported the discovery of covert anti-P antibodies and their masking …
The tectonic history of the southwestern United States and Sonora, Mexico, during the past 100 My
G Gastil, M Wracher, G Strand, L Lee Kear, D Eley… - …, 1992 - Wiley Online Library
The area between the Colorado Plateau on the north, New Mexico and Chihuahua to the
east, and southern and Baja California to the southwest has undergone a complicated …
east, and southern and Baja California to the southwest has undergone a complicated …
Development of the anti‐Ro autoantibody response in a patient with systemic lupus erythematosus
RH Scofield, F Zhang, BT Kurien… - … : Official Journal of …, 1996 - Wiley Online Library
Objective. To characterize the initial events in anti‐Ro production by a patient with systemic
lupus erythematosus, in whom this autoantibody is developing. Methods. The immune …
lupus erythematosus, in whom this autoantibody is developing. Methods. The immune …
Molecular thermodynamics for fluid‐phase equilibria in aqueous two‐protein systems
N von Solms, CO Anderson, HW Blanch… - AIChE …, 2002 - Wiley Online Library
With saline water as the continuous medium, a two‐component McMillan‐Mayer equation of
state is used to describe liquid–liquid phase equilibria in a two‐protein system. The equation …
state is used to describe liquid–liquid phase equilibria in a two‐protein system. The equation …
The presence of masked antiribosomal P autoantibodies in healthy children
CJ Anderson, BR Neas, Z Pan… - … : Official Journal of …, 1998 - Wiley Online Library
Objective To determine if antiribosomal P (anti‐P) autoantibodies are present in healthy
children. Methods Sera from healthy children were screened for anti‐P by conventional …
children. Methods Sera from healthy children were screened for anti‐P by conventional …
Cell polarity and neurogenesis in embryonic stem cell-derived neural rosettes
E Banda, A McKinsey, N Germain, J Carter… - Stem cells and …, 2015 - liebertpub.com
Embryonic stem cells (ESCs) undergoing neural differentiation form radial arrays of neural
stem cells, termed neural rosettes. These structures manifest many of the properties …
stem cells, termed neural rosettes. These structures manifest many of the properties …
Anti-Ro and concomitant anti-La autoantibodies strongly associated with anti-oxLDL or anti-phospholipid antibody in systemic lupus erythematosus
BT Kurien, J Fesmire, CJ Anderson… - JCR: Journal of Clinical …, 2016 - journals.lww.com
Background Premature atherosclerosis is observed in systemic lupus erythematosus (SLE).
Oxidative modification of LDL is associated with atherosclerotic plaque formation. Objectives …
Oxidative modification of LDL is associated with atherosclerotic plaque formation. Objectives …