The possible coexistence of supersensitivity and overinhibition (Schizophrenia: Origins, Processes, Treatment and Outcome (1993) 335-350) in schizophrenia was studied using the Adult Sensory Profile as a measure of Dunn's (Infants Young Children 9 (1997) 23-25) model of sensory processing. The quadrant model describes sensory sensitivity, sensation avoiding, low registration and sensation seeking as behavioral responses to sensation. Individuals with schizophrenia (N = 27), bipolar disorder (N = 30) and mentally healthy controls (N = 29) were compared using the Adult Sensory Profile. When compared to the mentally healthy group, the results indicated that both the schizophrenia group and the bipolar disorder group had higher scores on sensation avoiding. The schizophrenia group also had higher scores on low registration and lower scores on sensation seeking than the mentally health group. There were no differences between the schizophrenia and bipolar disorder group. According to the findings of this study, individuals with schizophrenia tend to miss available sensory stimuli. When stimuli are indeed detected, they are often avoided.