PT - JOURNAL ARTICLE AU - Charlotte Duffee TI - An intellectual history of suffering in the Encyclopedia of Bioethics, 1978–2014 AID - 10.1136/medhum-2019-011800 DP - 2021 Sep 01 TA - Medical Humanities PG - 274--282 VI - 47 IP - 3 4099 - http://mh.bmj.com/content/47/3/274.short 4100 - http://mh.bmj.com/content/47/3/274.full SO - J Med Humanit2021 Sep 01; 47 AB - Suffering is an important theme in many bioethical debates, yet little historical research is available to contextualise ideas about it. My article proposes a preliminary intellectual history of suffering in bioethics using the field’s most trusted tertiary work, the four editions of the Encyclopedia of Bioethics (1978–2004), later renamed Bioethics (2014). In the first edition, I find suffering roughly conceptualised as either the negation of a good or as a pain. The former acquired a technical connotation beginning in the second edition, when physician Eric Cassell refined the negative aspects of suffering into a full-fledged theory. Now, suffering no longer marked the loss of just any good but instead threatened one’s purpose in relation to that good. Cassell also strongly distinguished suffering from pain which, when combined with his theory of suffering, hardened earlier distinctions between pain and suffering that were present but weak in the first encyclopedia. Both Cassell’s theory and his strong distinction impacted how other contributors moralised suffering in the later encyclopedias, although his influence was not total: utilitarians continued to moralise suffering in ways that still roughly construed it as pain. Consequently, Cassell and the utilitarians conflicted conceptually. Nevertheless, this tension went unfelt in the encyclopedias for reasons I describe. I close by suggesting areas for further historical research and argue for their relevance to bioethical enquiries into suffering.Data sharing not applicable as no datasets generated and/or analysed for this study.